SQLite looks more portable, but I know that MySQL is heavier (i use it in web development). MySQL needs more resources.
SQLite does not require any configuration, just turn it on in RadioBOSS settings and that's it. MySQL requires you to install the database (MySQL or, better, MariaDB) and input connection information into RadioBOSS.
In terms of resources, there's no difference between the two, we've tested it on huge databases and it performed very well.